Title: Physeo Anki Decks / 04 - Biochemistry / 04 - Genetics / Section 09.4 - Friedreich Ataxia

Q: Friedreich ataxia results in a [characteristic gait] with frequent falls
A: staggering gait
Extra: Gate = Staggering gait

Q: Friedreich Ataxia is assocaited with [which cardiomyopathy]
A: hypertrophic cardiomyopathy
Extra: Thick armored cart = Hypertrophic cardiomyopathy

Q: Friedreich ataxia can result in [...], an abnormal bend in the middle joint of the toes
A: hammer toes
Extra: Hammer dropped on toes = Hammer toes

Q: Friedreich Ataxia is associated with [...], characterized by repetitive, uncontrolled eye movements
A: nystagmus
Extra: Punched in the face with eyes spinning = Nystagmus

Q: Friedreich ataxia results in a staggering gait with frequent [...]
A: falls
Extra: Guy falling off later = Frequent falls

Q: Friedreich Ataxia results in degeneration of 3 neural tracts:
1.) [...] - Fine touch, vibration, proprioception
2.) Spinocerebellar tract - transmitts propiocetive information to ipilateral cerebellum
3.) Lateral corticospinal tract - voluntary motor to anterior horn
A: Dorsal column
Extra: Pillars/Columns = Dorsal column

Q: Friedreich Ataxia results in degeneration of 3 neural tracts:
1.) Dorsal column - Fine touch, vibration, proprioception
2.) [...] - Propiocetive information to ipilateral cerebellum
3.) Lateral corticospinal tract - Voluntary motor to anterior horn
A: Spinocerebellar tract
Extra: Spines = Spinocerebellar tract

Q: Friedreich Ataxia results in degeneration of 3 neural tracts:
1.) Dorsal column - Fine touch, vibration, proprioception
2.) Spinocerebellar tract - transmitts propiocetive information to ipilateral cerebellum
3.) [...] - voluntary motor to anterior horn
A: Lateral corticospinal tract
Extra: Ladder = Lateral corticospinal tract

Q: Friedreich ataxia is assocaited with [metabolic disorder]
A: diabetes mellitus
Extra: Dyed beads = Diabetes mellitus

Q: Friedreich Ataxia is associated with [...], characterized by a foot with a high arch
A: pes cavus
Extra: Tippy toes = Pes cavus

Q: Friedreich Ataxia is assocated with [...], excessive anterior and lateral spine misalignment
A: kyphoscoliosis
Extra: Crooked line of skulls = Kyphoscoliosis

Q: [condition] results from a defective [gene] ([protein type]), resulting in mitochondrial dysfunction
A: Friedreich Ataxia; Frataxin gene; iron binding protein
Extra: Federal tax enforcement building with protective iron bars = Frataxin gene is an iron binding protein

Q: Friedreich Ataxia causes with impaired speech articulation leading to [...]
A: dysarthria
Extra: GA abolitionist = GAA repeat