Title: Physeo Anki Decks / 02 - Physiology / 06 - Endocrinology / Section 08 - Congenital Adrenal Hyperplasias

Q: 17α-hydroxylase deficiency will lead to [increased or decreased] cortisol and [increased or decreased] testosterone
A: decreased; decreased

Q: 17α-hydroxylase deficiency will lead to [increased or decreased] aldosterone
A: increased

Q: 17α-hydroxylase deficiency will result in metabolic [acidosis or alkalosis]
A: alkalosis

Q: 17α-hydroxylase will lead to [hyper or hypokalemia]
A: hyperkalemia

Q: [21 or 17α] hydroxylase deficiency will lead to increased blood pressure (initially)
A: 17α

Q: 17α-hydroxylase deficiency will lead to [increased or decreased] androgen production
A: decreased

Q: 21-hydroxylase deficiency will lead to [increased or decreased] cortisol and aldosterone
A: decreased

Q: Increased androgen production will be seen with [congenital adernal hyperplasia]
A: 21-hydroxylase deficiency

Q: 21-hydroxylase deficiency will present with [high or low] blood pressure
A: low

Q: Increased progesterone will be seen in [congenital adrenal hyperplasia]
A: 21-hydroxylase deficiency

Q: Metabolic acidosis will be seen with [congenital adrenal hyperplasia]
A: 21-hydroxylase deficiency

Q: low blood pressure and shock are manifestations of [congenital adrenal hyperplasia]
A: 21-hydroxylase deficiency

Q: 11ß-hydroxylase deficiency will lead to [increased or decreased] aldosterone
A: decreased
Extra: however, there is an increase in 11-deoxycorticosterone which acts as aldosterone

Q: ↓Cortisol → [increased or decreased] ACTH → adrenal hyperplasia
A: ↑

Q: Increased aldosterone will lead to [increased or decreased] K^+ levels
A: decreased

Q: Females with 21-hydroxylase deficiency will have [genitalia finding] at birth
A: ambigous genitalia

Q: females with 17α-hydroxylase deficiency will have [genitalia finding] at birth
A: normal genitalia

Q: Precocious puberty occurs in both [(2) congenital adrenal hyperplasia]
A: 11ß and 21 hydroxylase deficiency
Extra: Not seen with 17α-hydroxylase deficiency

Q: Salt wasting hypovolemia and shock occur when aldosterone levels are [high or low]
A: low