Title: Physiology / 01 General Principles / Section 1 - Cell Transport
Tags: Physeo::01Physeo_General_Principles::01Physeo_Cellular_Transport

Q: The three types of carrier mediated transport are:
[...]
A: 1. Facilitated diffusion
2. Primary active transport
3. Secondary active transport

Q: Facilitated diffusion uses a [...] for transport across the membrane.
A: carrier protein/transporter

Q: Facilitated diffusion [does or does not] require energy
A: does not
Extra: Passive -- any time you see diffusion  think passive, and it will therefore follow its concentration gradient.

Q: Almost any substance that cannot enter via simple diffusion can [...]
A: use faciliated diffusion
Extra: Diffusion = passive
(AKA hydrophilic things can use facilitated diffusion)

Q: Primary active transport requires (2)[...] in order to move a substance against its gradient.
A: ATP and a carrier protein
Extra: carrier mediated, active (ATP)
H+ is transported against its gradient in the parietal cells to keep the chyme acidic in the stomach lumen.

Q: Secondary active transport requires a carrier protein and ATP. It moves against the gradient in question but follows the [...] created by 1* active transport
A: Na+ gradient
Extra: therefore glucose flows into cell (symport)
OR
calcium goes out of cell (antiport)

Q: Iron in the serum forms a transferrin-iron complex, which stimulates  [...]
A: receptor mediated endocytosis
Extra: RME is how iron-tf gets into cells

Q: LDL stimulates LDLRs, which increases [...]
A: receptor mediated endocytosis

Q: EGF stimulates EGFRs, which increases [...]
A: receptor mediated endocytosis

Q: LDLR is dysfunctional, therefore the intracellular level of LDL in adipose tissue will [increase or decrease?]
A: decrease.
Extra: it decreases endocytosis and decreases intracellular level of LDL, increases extracellular level of LDL who can go to places in the body that it shouldn't -- this is hypercholesterolemia type IIa